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More about the Latest Journals
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Audio Summary, (Latest) |
| Description: Low-Molecular-Weight Heparin versus Compression Stockings for Thromboprophylaxis after Knee Arthroscopy: A Randomized Trial
Giuseppe Camporese, Enrico Bernardi, Paolo Prandoni, Franco Noventa, Fabio Verlato, Paolo Simioni, Kadimashi Ntita, Giovanna Salmistraro, Christos Frangos, Franco Rossi, Rosamaria Cordova, Francesca Franz, Pietro Zucchetta, Dimitrios Kontothanassis, Giuseppe Maria Andreozzi for the KANT (Knee Arthroscopy Nadroparin Thromboprophylaxis) Study Group
In this trial, 1761 adults who had knee arthroscopy were randomly assigned to receive 7 or 14 days of low-molecular-weight heparin (LMWH) or to wear a full-length graduated compression stocking on the operated leg for 1 week. Fewer than 1% of the patients in any group had significant postsurgical bleeding complications. Fewer patients in the 7-day LMWH group experienced a composite outcome of deep venous thrombosis, pulmonary embolism, or death.
Empirical Fluconazole versus Placebo for Intensive Care Unit Patients: A Randomized Trial
Mindy G. Schuster, John E. Edwards, Jr., Jack D. Sobel, Rabih O. Darouiche, Adolf W. Karchmer, Susan Hadley, Gus Slotman, Helene Panzer, Pinaki Biswas, and John H. Rex
This multicenter trial tested the effect of empirical antifungal treatment in febrile intensive care unit patients. Investigators randomly assigned 270 patients with fever despite taking broad-spectrum antibiotics to either fluconazole, 800 mg/d, or placebo for 2 weeks. About 40% of patients in each group achieved all 4 components of successful treatment: resolution of fever, no invasive fungal infection, no stopping therapy because of toxicity, and no need for a nonstudy systemic antifungal medication. Compared with placebo, empirical antifungal fluconazole therapy had no effect in high-risk intensive care unit patients.
Prehypertension during Young Adulthood and Coronary Calcium Later in Life
Mark J. Pletcher, Kirsten Bibbins-Domingo, Cora E. Lewis, Gina S. Wei, Steve Sidney, J. Jeffrey Carr, Eric Vittinghoff, Charles E. McCulloch, and Stephen B. Hulley
In their prospective cohort study, Pletcher and colleagues found that prehypertension before age 35 years, especially systolic prehypertension, showed a graded association with coronary calcium later in life. This association remained strong after adjustment for differences in blood pressure elevation after age 35 years and other coronary risk factors and participant characteristics.
Improving Patient Care Back
Comparing Patient-Reported Hospital Adverse Events with Medical Record Review: Do Patients Know Something That Hospitals Do Not?
Joel S. Weissman, Eric C. Schneider, Saul N. Weingart, Arnold M. Epstein, JoAnn David-Kasdan, Sandra Feibelmann, Catherine L. Annas, Nancy Ridley, Leslie Kirle, and Constantine Gatsonis
Little is known about whether patient interviews can reveal adverse events not detected by medical record review. Weissman and colleagues compared adverse event rates from postdischarge patient interviews with those from medical records. Among 998 study patients, 23% had at least 1 adverse event detected by interview, compared with 11% by record review. Record review identified 11 serious and preventable events. Interviews identified 21 serious and preventable events that were not documented in the medical record. Hospitals should consider adding questions about adverse events to postdischarge interviews. |
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Medical Podcast, (July 1, 2008) |
| Description:
Early-Release Article: 1 July 2008
Systematic Review: T-Cell–Based Assays for the Diagnosis of Latent Tuberculosis Infection: An Update
Pai, Zwerling, and Menzies
Print Issue: 1 July 2008
ARTICLES
Diabetes and Hearing Impairment in the United States: Audiometric Evidence from the National Health and Nutrition Examination Survey, 1999 to 2004
Bainbridge, Hoffman, and Cowie
The Effect of Comorbid Illness and Functional Status on the Expected Benefits of Intensive Glucose Control in Older Patients with Type 2 Diabetes: A Decision Analysis
Huang, Zhang, Gandra, Chin, and Meltzer
Relationship of Specific Vaginal Bacteria and Bacterial Vaginosis Treatment Failure in Women Who Have Sex with Women
Marrazzo, Thomas, Fiedler, Ringwood, and Fredricks
IMPROVING PATIENT CARE
Public Reporting of Antibiotic Timing in Patients with Pneumonia: Lessons from a Flawed Performance Measure
Wachter, Flanders, Fee, and Pronovost
REVIEW
Meta-analysis: Effects of Adding Salmeterol to Inhaled Corticosteroids on Serious Asthma-Related Events
Bateman, Nelson, Bousquet, Kral, Sutton, Ortega, and Yancey
Click here for this article's CME course.
PERSPECTIVE
Surrogate Decision Making: Reconciling Ethical Theory and Clinical Practice
Berger, DeRenzo, and Schwartz
CLINICAL GUIDELINES
Screening for Asymptomatic Bacteriuria in Adults: U.S. Preventive Services Task Force Reaffirmation Recommendation Statement
U.S. Preventive Services Task Force
Screening for Asymptomatic Bacteriuria in Adults: Evidence for the U.S. Preventive Services Task Force Reaffirmation Recommendation Statement
Lin and Fajardo
EDITORIALS
Hearing Loss and Diabetes: You Might Not Know What You're Missing
Hirose
Drug Safety and Salmeterol: The Controversy Continues |
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The Mystery of Increased Hospitalizations of Elderly Patients, (Latest) |
| Description: Pneumonia is a common illness that affects millions of people in the United States every year. In some people, particularly the elderly and those who are ill from pre-existing conditions, bacterial pneumonia may follow influenza or even a common cold. Dr. Martin Meltzer, discusses two articles in the May 2008 issue of Emerging Infectious Diseases journal about increased pneumonia-related hospitalizations of elderly patients in England. |
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Cover Artwork Slowing the Next Pandemic: Survey of Community Mitigation Strategies - Podcast, (May 20, 2008) |
| Description: During the next influenza pandemic, it will take time to develop a vaccine and there may be limited medication to treat or prevent illness. To slow the spread of disease, CDC and other public health officials will likely ask Americans to decrease contact with others through altering work schedules, school dismissals and other measures. Researchers recently surveyed the public to see whether people could follow those recommendations and what kind of impact they might have. |
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Dengue Fever Seroprevalence and Risk Factors, Texas–Mexico Border, 2004, (October 1, 2007) |
| Description: Dengue fever is both endemic and underrecognized along a section of the southern Texas–Mexico border, and low income is a primary risk factor for infection. As part of a special section on Global Poverty and Human Development, Dr. Joan Marie Brunkard discusses a dengue seroprevalence survey in this region and what can be done to help prevent infection and to identify and treat those who are infected. |
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Increase in Clostridium difficile–related Mortality Rates, United States, 1999–2004, (September 1, 2007) |
| Description: Deaths related to Clostridium difficile are on the rise in the United States. Matthew Redelings from the Los Angeles County Department of Health discusses the increase and what can be done to prevent this infection. |
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June, (Latest) |
| Description: Summary of June EBM featuring Cochrane Reviews in general medicine, obstetrics, and diabetes this month. |
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June, (June 15, 2008) |
| Description: Summary of June EBM featuring Cochrane Reviews in general medicine, obstetrics, and diabetes this month. |
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Audio Commentary, (Latest) |
| Description: * Hypericum perforatum (St John's Wort) for Attention-Deficit/Hyperactivity Disorder in Children and Adolescents: A Randomized Controlled Trial Free
* Effect of Bright Light and Melatonin on Cognitive and Noncognitive Function in Elderly Residents of Group Care Facilities: A Randomized Controlled Trial
* Clinical Implications of QRS Duration in Patients Hospitalized With Worsening Heart Failure and Reduced Left Ventricular Ejection Fraction
Clinician's Corner: Perspectives on Care at the Close of Life
* The Role of Chemotherapy at the End of Life: "When Is Enough, Enough?" CME
* CME Course
Commentaries
* Confronting the Complexity of the Physician Workforce Equation
* Biofilms and Chronic Infections
Editorial
* Quality of Efficacy Research in Complementary and Alternative Medicine
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Listen to the Lancet, (Latest) |
| Description: Pam Das and Sally Hargreaves discuss highlights from the August issue of The Lancet Infectious Diseases ahead of the World AIDS meeting in Mexico next month. |
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Listen to the Lancet, (July 1, 2008) |
| Description: MRSA, typhus, and STOP TB: Hospital-acquired MRSA, the potential bioterrorism threat of typhus, and an analysis of the STOP TB partnership are discussed in a podcast. |
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Listen to the Lancet, (May 27, 2008) |
| Description: The June issue of The Lancet Infectious Diseases includes discussion of the female condom, introduced in Europe 15 years ago, but still a neglected tool for protection against pregnancy and sexually transmitted infections, especially HIV. Sally Hargreaves discusses the potential role of the female condom, including its use in areas with high HIV prevalence, with Susie Hoffman and Theresa Exner, from Columbia University, New York City, USA, in this month's podcast. |
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Listen to the Lancet, (Latest) |
| Description: The Lancet Neurology podcast: Helen Frankish discusses biomarkers for indications of dementia, and other highlights from the August issue.. |
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Listen to the Lancet, (June 28, 2008) |
| Description: The International LRRK2 Consortium, which includes investigators in 21 centres, has collected data from almost 20000 patients with Parkinson's disease carrying mutations in the LRRK2 gene. The Lancet Neurology editor Elena Becker-Barroso and Daniel Healy, the corresponding author on their first report, summarises the findings and their implications in clinical practice in a podcast. |
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Listen to the Lancet, (June 21, 2008) |
| Description: The International LRRK2 Consortium, which includes investigators in 21 centres, has collected data from almost 20000 patients with Parkinson's disease carrying mutations in the LRRK2 gene. The Lancet Neurology editor Elena Becker-Barroso and Daniel Healy, the corresponding author on their first report, summarises the findings and their implications in clinical practice in a podcast. |
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Listen to the Lancet, (Latest) |
| Description: The Lancet Oncology podcast: a global health theme for the August issue. Editor David Collingridge discusses the highlights, including cancer survival from five continents, and a review of cancer issues in Africa. |
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Listen to the Lancet, (July 1, 2008) |
| Description: TLO Editor David Collingridge discusses some highlights from the July issue: radiofrequency ablation showing promise for the treatment of lung cancer; how a rare form of obesity could negatively affect treatment outcomes; and a discussion of a recent meeting at IARC in Lyon, France, concerning the latest evidence on smoke-free policies and the effects on public health. |
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Listen to the Lancet, (June 1, 2008) |
| Description: Emma Cannell and Sally van der Meer discuss highlights from the June issue: a prospective pilot study assessing the role of stellate-ganglion block to treat hot flushes in survivors of breast cancer; also discussed is a Personal View about cancer of unknown primary (CUP), and the Leading Edge on public confidence in Merck's HPV vaccine. |
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Jul 15